England XV (19) 24
Tries: Willis, Coles, Carpenter, Dombrandt Cons: Ford 2
France XV (12) 26
Tries: Barlot, Auradou, Mallez, Taofifenua Cons: Le Garrec 3
Immanuel Feyi-Waboso was sent off as Steve Borthwick's England XV conceded two late tries in a disappointing 26-24 defeat by a France XV at Twickenham's Allianz Stadium.
A try from Harlequins captain Alex Dombrandt moments after France's Cameron Woki was sent off gave England a 24-12 lead heading into the final 10 minutes.
However, France scored from close range to set up a frantic final five minutes and the visitors' pressure paid off when Romain Taofifenua burrowed over to tie the scores with the clock in the red.
Fly-half Antoine Hastoy fired over the conversion to snatch victory for Fabien Galthie's side with the last kick of an energy-sapping match played in sweltering conditions in London.
Feyi-Waboso, who missed the Six Nations and a possible place in the British and Irish Lions squad after dislocating his shoulder in December, was shown a yellow card in the 34th minute for tackling Hastoy around the neck.
After a straightforward review, the card was upgraded to a 20-minute red because of the high degree of danger and lack of mitigation.
England had fought back after conceding two early tries to lead at half-time thanks to tries from Tom Willis, Alex Coles and Joe Carpenter, but will rue the way they let France back into the game in the closing stages.
Borthwick, who was without the 13 players selected in the Lions squad - including captain Maro Itoje - names his squad to tour Argentina and the United States on Monday.
England XV: Carpenter; Roebuck, Slade, Atkinson, Feyi-Waboso; Ford (co-capt), Spencer; Baxter, George (co-capt), Heyes, Coles, Isiekwe, Hill, Pepper, Willis
Replacements: Dan, Rodd, Davison, Cunningham-South, Kenningham, Dombrandt, Quirke, Beard
Red card: Feyi-Waboso (34)
France XV: Attissogbe; Moustin, Gailleton, Fickou, Duguivalu; Hastoy, Le Garrec; Erdocio, Barlot, Slimani, Auradou, Duguid, Fishcher, Tixeront, Guillard.
Replacements: G Marchand, Mallez, Bamba, Taofifenua, Van Tonder, Woki, Jauneau, Berdeu
Red card: Cameron Woki (54)
Referee: Hollie Davidson (Sco)
Assistant referees: Eoghan Cross (Ire) and Sam Grove White (Sco)
TMO: Mike Adamson (Sco)
English (US) ·